Protein Technologies launched its newest peptide synthesizer, the OVERTURE Robotic Peptide Library Synthesizer, at Pittcon 2010. The OVERTURE can run syntheses from 0.005 to 24 mmol scales. It features six reaction blocks capable of holding 96 (10 mL) or 24 (40 or 45 mL) reaction vessels, 49 amino acid positions, six solvent bottle positions, variable-speed vortex mixing, automatic robotic arm calibration, and a full-color chemical-resistant touchscreen. Amino acid deliveries are performed from individual dispensers, which do not require rinsing in between deliveries, saving the user money and time. These dispensers are capable of infinitely variable delivery volumes accurate to 50 µL. The OVERTURE’s software features sequence importing, automatic sequence placement, automatic library generation, automated cleaning routines, and report and log file generation. Special features include the Safe-Response feature which automatically drains and rinses the resin with solvent when an error occurs, as well as E-mail Notification which can send an email or a text message to a computer or cell phone with the status of a synthesis, for worry-free operation. Other features include a workstation utility, which allows syntheses to be created on a desktop computer, and then transferred to the OVERTURE with a USB stick. A door-opening mechanism saves bench space, and an optional solvent cabinet configuration is also available. Protein Technologies, Inc., 800-477-6834, www.peptideinstruments.com